diff --git a/packages/jest-preset/jest/__tests__/setup-test.js b/packages/jest-preset/jest/__tests__/setup-test.js
index 8e8daed7caf4..dcde537690c9 100644
--- a/packages/jest-preset/jest/__tests__/setup-test.js
+++ b/packages/jest-preset/jest/__tests__/setup-test.js
@@ -10,6 +10,31 @@
 
 import NativeExceptionsManager from 'react-native/Libraries/Core/NativeExceptionsManager';
 
+test('NativeAnimatedHelper is a mock', () => {
+  const consoleWarn = jest.spyOn(console, 'warn').mockImplementation(() => {});
+
+  try {
+    const NativeAnimatedHelper: {
+      assertNativeAnimatedModule: () => void,
+      nativeEventEmitter: {addListener: () => void},
+      shouldUseNativeDriver: () => boolean,
+    } = jest.requireMock(
+      'react-native/src/private/animated/NativeAnimatedHelper',
+    ).default;
+
+    expect(
+      jest.isMockFunction(NativeAnimatedHelper.assertNativeAnimatedModule),
+    ).toBe(true);
+    expect(NativeAnimatedHelper.nativeEventEmitter).toBeDefined();
+    expect(
+      jest.isMockFunction(NativeAnimatedHelper.shouldUseNativeDriver),
+    ).toBe(false);
+    expect(consoleWarn).not.toHaveBeenCalled();
+  } finally {
+    consoleWarn.mockRestore();
+  }
+});
+
 test('NativeExceptionsManager is a mock', () => {
   expect(jest.isMockFunction(NativeExceptionsManager.reportException)).toBe(
     true,
diff --git a/packages/jest-preset/jest/mocks/NativeAnimatedHelper.js b/packages/jest-preset/jest/mocks/NativeAnimatedHelper.js
new file mode 100644
index 000000000000..da2acd07c47e
--- /dev/null
+++ b/packages/jest-preset/jest/mocks/NativeAnimatedHelper.js
@@ -0,0 +1,22 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ * @flow strict-local
+ * @format
+ */
+
+import typeof TNativeAnimatedHelper from 'react-native/src/private/animated/NativeAnimatedHelper';
+
+const NativeAnimatedHelper = jest.requireActual<{
+  default: TNativeAnimatedHelper,
+}>('react-native/src/private/animated/NativeAnimatedHelper').default;
+
+const NativeAnimatedHelperMock: TNativeAnimatedHelper = {
+  ...NativeAnimatedHelper,
+  assertNativeAnimatedModule: jest.fn(),
+};
+
+export default NativeAnimatedHelperMock;
diff --git a/packages/jest-preset/jest/setup.js b/packages/jest-preset/jest/setup.js
index 5082aece44fe..5e9935494a0e 100644
--- a/packages/jest-preset/jest/setup.js
+++ b/packages/jest-preset/jest/setup.js
@@ -176,3 +176,7 @@ mock(
   // $FlowFixMe[incompatible-type]
   'm#./mocks/Vibration',
 );
+mock(
+  'm#react-native/src/private/animated/NativeAnimatedHelper',
+  'm#./mocks/NativeAnimatedHelper',
+);