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cff-version: 1.2.0
message: "If you use CRAFT in your research, please cite the manuscript below."
title: "A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling"
type: software
license: MIT
repository-code: "https://github.com/KarchinLab/CRAFT"
doi: 10.5281/zenodo.19891746
url: "https://doi.org/10.5281/zenodo.19891746"
authors:
- family-names: Balan
given-names: Archana
affiliation: "Institute for Computational Medicine, Johns Hopkins University; Department of Biomedical Engineering, Johns Hopkins University; Department of Oncology, Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine"
- family-names: Elhanati
given-names: Yuval
affiliation: "Computational Oncology Service, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center"
- family-names: Meza Landeros
given-names: Kevin E.
affiliation: "Institute for Computational Medicine, Johns Hopkins University; Department of Biomedical Engineering, Johns Hopkins University"
- family-names: De Almeida Mendes
given-names: Marcus
affiliation: "Institute for Computational Medicine, Johns Hopkins University; Department of Oncology, Johns Hopkins University School of Medicine"
- family-names: Lai
given-names: Jiaying
affiliation: "Institute for Computational Medicine, Johns Hopkins University"
- family-names: Ali Zaidi
given-names: Syed Shujaat
affiliation: "Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center"
- family-names: Unal
given-names: Mesut
affiliation: "Department of Neurosurgery Research, The University of Texas MD Anderson Cancer Center"
- family-names: Kim
given-names: Betty Y.S.
affiliation: "James P. Allison Institute, The University of Texas MD Anderson Cancer Center; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center"
- family-names: Lucas
given-names: Calixto-Hope G.
affiliation: "Department of Pathology, Johns Hopkins University School of Medicine"
- family-names: Runco
given-names: Emerenziana
affiliation: "Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School"
- family-names: Puduvalli
given-names: Vinay K.
affiliation: "Department of Neuro-Oncology, Center for Neurosciences of Cancer, The University of Texas MD Anderson Cancer Center"
- family-names: Gantchev
given-names: Jennifer
affiliation: "Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School"
- family-names: Whittaker
given-names: Charles A.
affiliation: "Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology"
- family-names: Sharma
given-names: Pratibha
affiliation: "Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center"
- family-names: Tabar
given-names: Viviane
affiliation: "Department of Neurosurgery, Memorial Sloan Kettering Cancer Center"
- family-names: Cima
given-names: Michael J.
affiliation: "Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology"
- family-names: Baquer
given-names: Gerard
affiliation: "Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School"
- family-names: Reardon
given-names: David A.
affiliation: "Center for Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School"
- family-names: Stortchevoi
given-names: Alexei
affiliation: "Department of Biology, Massachusetts Institute of Technology"
- family-names: Boire
given-names: Adrienne
affiliation: "Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center"
- family-names: Wang
given-names: Linghua
affiliation: "Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center"
- family-names: White
given-names: Forest M.
affiliation: "Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology"
- family-names: Sidiropoulos
given-names: Dimitrios N.
affiliation: "Department of Oncology, Johns Hopkins University School of Medicine"
- family-names: Yu
given-names: Kenny Kwok Hei
affiliation: "Department of Neurosurgery, Memorial Sloan Kettering Cancer Center"
- family-names: Chiocca
given-names: E. Antonio
affiliation: "Department of Neurosurgery, Mass General Brigham"
- family-names: Anagnostou
given-names: Valsamo
affiliation: "Department of Oncology, Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine"
- name: "Data Science Teamlab"
- name: "Accelerating GBM Therapies TeamLab"
- family-names: Karchin
given-names: Rachel
email: karchin@jhu.edu
affiliation: "Institute for Computational Medicine, Johns Hopkins University; Department of Biomedical Engineering, Johns Hopkins University; Department of Oncology, Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine"
preferred-citation:
type: article
title: "A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling"
authors:
- family-names: Balan
given-names: Archana
- family-names: Karchin
given-names: Rachel
# journal: "Nature Methods"
# year: 2026
# doi: 10.XXXX/XXXXXX # FILL IN after Nature Methods accession is minted
# url: "https://doi.org/10.XXXX/XXXXXX"
# Preprint (bioRxiv): FILL IN after preprint deposition.